Comparative Annotation Toolkit (CAT)—simultaneous clade and personal genome annotation
نویسندگان
چکیده
منابع مشابه
Comparative Genome Annotation Systems
Understanding the genetic content of a genome is a very important but challenging task. One of the most effective methods to annotate a genome is to compare it to the genomes that are already sequenced and annotated. This chapter is to survey systems that can be used for annotating genomes by comparing multiple genomes and discusses important issues in designing genome comparison systems such a...
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This lecture and the next will discuss the recent and current research in comparative genomics being performed in Professor Kellis’ lab. Comparative genomics allows one to infer understanding of genomes from the study of the evolution of closely related species, and vice-versa. This lecture will discuss the use of evolution to understand genomes, and lecture 16 will deal with using genomes to b...
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The Annotation Graph Toolkit is a collection of software supporting the development of annotation tools based on the annotation graph model. The toolkit includes application programming interfaces for manipulating annotation graph data and for importing data from other formats. There are interfaces for the scripting languages Tcl and Python, a database interface, specialized graphical user inte...
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SNPedia (http://www.SNPedia.com) is a wiki resource of the functional consequences of human genetic variation as published in peer-reviewed studies. Online since 2006 and freely available for personal use, SNPedia has focused on the medical, phenotypic and genealogical associations of single nucleotide polymorphisms. Entries are formatted to allow associations to be assigned to single genotypes...
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MOTIVATION The massively parallel sequencing technology can be used by small research labs to generate genome sequences of their research interest. However, annotation of genomes still relies on the manual process, which becomes a serious bottleneck to the high-throughput genome projects. Recently, automatic annotation methods are increasingly more accurate, but there are several issues. One im...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2018
ISSN: 1088-9051,1549-5469
DOI: 10.1101/gr.233460.117